Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Dry eye
ADR ID BADD_A01343
ADR Hierarchy
06      Eye disorders
06.08      Eye disorders NEC
06.08.02      Lacrimation disorders
06.08.02.001      Dry eye
Description A disorder characterized by dryness of the cornea and conjunctiva. [CTCAE] Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur. [MeSH]
MedDRA Code 10013774
MeSH ID D015352; D007638
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Conjunctival xerosis | Dry eye | Dry eye NOS | Dry eye syndrome | Dry eyes | Dryness of eyes | Dryness under lids | Eye dryness | Eyes dry | Keratoconjunctivitis sicca | Keratoconjunctivitis sicca, not specified as Sjogren's | Dry eyes aggravated | Keratitis sicca | Corneal xerosis | Lacrimal gland insufficiency | Dry Eye Syndromes | Dry Eye Syndrome | Syndrome, Dry Eye | Syndromes, Dry Eye
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02498Abemaciclib0.000951%
BADD_D02500Alpelisib0.000571%
BADD_D02506Erdafitinib0.000940%
BADD_D02507Deutetrabenazine0.001830%
BADD_D02510Rucaparib0.000884%
BADD_D02524Ivosidenib0.000381%
BADD_D02558Gadolinium cation (3+)-
BADD_D02565Lumateperone0.000444%
BADD_D02573Mobocertinib0.000112%
BADD_D02579Oxymetazoline0.010843%
BADD_D02619Dienogest--
BADD_D02623Hydrogen peroxide--
BADD_D02628Myristamidopropyl dimethylamine--
BADD_D02633Propylene glycol--
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