Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Dry eye
ADR ID BADD_A01343
ADR Hierarchy
06      Eye disorders
06.08      Eye disorders NEC
06.08.02      Lacrimation disorders
06.08.02.001      Dry eye
Description A disorder characterized by dryness of the cornea and conjunctiva. [CTCAE] Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur. [MeSH]
MedDRA Code 10013774
MeSH ID D015352; D007638
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Conjunctival xerosis | Dry eye | Dry eye NOS | Dry eye syndrome | Dry eyes | Dryness of eyes | Dryness under lids | Eye dryness | Eyes dry | Keratoconjunctivitis sicca | Keratoconjunctivitis sicca, not specified as Sjogren's | Dry eyes aggravated | Keratitis sicca | Corneal xerosis | Lacrimal gland insufficiency | Dry Eye Syndromes | Dry Eye Syndrome | Syndrome, Dry Eye | Syndromes, Dry Eye
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01280Levomilnacipran hydrochloride--
BADD_D01281Levonorgestrel--
BADD_D01285Levothyroxine0.000044%
BADD_D01290Lifitegrast0.083055%
BADD_D01307Lodoxamide--
BADD_D01308Lodoxamide tromethamine--
BADD_D01319Lorcaserin hydrochloride--
BADD_D01320Lorcaserin hydrochloride hemihydrate--
BADD_D01324Loteprednol etabonate0.000732%
BADD_D01326Loxapine--
BADD_D01366Medroxyprogesterone acetate--
BADD_D01397Mesalamine0.000622%
BADD_D01431Methylphenidate--
BADD_D01445Metoprolol0.000020%
BADD_D01446Metoprolol succinate--
BADD_D01447Metoprolol tartrate--
BADD_D01475Mirabegron0.001339%
BADD_D01476Mirtazapine--
BADD_D01490Mometasone0.000160%
BADD_D01491Mometasone furoate0.002179%
BADD_D01496Montelukast--
BADD_D01498Morphine--
BADD_D01501Moxifloxacin0.000458%
BADD_D01502Moxifloxacin hydrochloride--
BADD_D01508Mycophenolic acid--
BADD_D01510Nabilone--
BADD_D01512Nadolol--
BADD_D01533Naproxen--
BADD_D01535Naratriptan--
BADD_D01536Naratriptan hydrochloride--
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