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ADR Term
ADReCS ID
MedDRA Code
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ADR Ontology
ADR Term
Epiphyses premature fusion
ADR ID
BADD_A01525
ADR Hierarchy
05
Endocrine disorders
05.05
Endocrine disorders of gonadal function
05.05.03
Endocrine abnormalities of puberty
05.05.03.002
Epiphyses premature fusion
15
Musculoskeletal and connective tissue disorders
15.02
Bone disorders (excl congenital and fractures)
15.02.02
Epiphyseal disorders
15.02.02.001
Epiphyses premature fusion
Description
Not Available
MedDRA Code
10015078
MeSH ID
Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Closure premature epiphysis | Epiphyseal early closing | Epiphyses premature fusion | Epiphysis closure premature | Premature epiphyseal closure | Advanced bone age | Growth plate early closing
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D01213
Isotretinoin
0.005017%
BADD_D01431
Methylphenidate
0.000041%
BADD_D01530
Nandrolone decanoate
-
-
BADD_D01634
Oxandrolone
-
-
BADD_D01647
Oxymetholone
-
-
BADD_D02170
Testosterone
-
-
BADD_D02365
Vismodegib
0.000168%
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