Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Facial paralysis
ADR ID BADD_A01601
ADR Hierarchy
17      Nervous system disorders
17.04      Cranial nerve disorders (excl neoplasms)
17.04.03      Facial cranial nerve disorders
17.04.03.008      Facial paralysis
Description Severe or complete loss of facial muscle motor function. This condition may result from central or peripheral lesions. Damage to CNS motor pathways from the cerebral cortex to the facial nuclei in the pons leads to facial weakness that generally spares the forehead muscles. FACIAL NERVE DISEASES generally results in generalized hemifacial weakness. NEUROMUSCULAR JUNCTION DISEASES and MUSCULAR DISEASES may also cause facial paralysis or paresis. [MeSH]
MedDRA Code 10016062
MeSH ID D005158
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Facial droop | Facial palsy | Facial paralysis | LMNL of VIIth nerve | Paralysis facial | UMNL of VIIth nerve | Facial palsy aggravated | VIIth nerve paralysis | VIIth nerve palsy | Facial nerve paralysis | Facioplegia | Facial Paralysis | Paralyses, Facial | Paralysis, Facial | Facial Palsy | Facial Palsies | Palsies, Facial | Palsy, Facial | Hemifacial Paralysis | Paralyses, Hemifacial | Paralysis, Hemifacial | Facial Paresis | Pareses, Facial | Paresis, Facial | Facial Palsy, Lower Motor Neuron | Lower Motor Neuron Facial Palsy | Facial Paralysis, Peripheral | Facial Paralyses, Peripheral | Paralysis, Peripheral Facial | Peripheral Facial Paralysis | Facial Palsy, Upper Motor Neuron | Upper Motor Neuron Facial Palsy | Facial Paralysis, Central | Central Facial Paralyses | Central Facial Paralysis | Facial Paralyses, Central | Paralyses, Central Facial | Paralysis, Central Facial
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01922Regorafenib0.000224%
BADD_D01933Ribavirin0.024526%
BADD_D01942Riluzole--
BADD_D01951Risperidone0.000727%
BADD_D01954Rivaroxaban0.000760%
BADD_D02006Selexipag0.000082%
BADD_D02016Sibutramine--
BADD_D02026Simvastatin0.000018%
BADD_D02031Sitaxentan--
BADD_D02039Sodium fluoride--
BADD_D02058Sorafenib0.000280%
BADD_D02093Sulfasalazine0.000303%
BADD_D02098Sumatriptan--
BADD_D02099Sumatriptan succinate--
BADD_D02104Tacrine hydrochloride--
BADD_D02105Tacrolimus0.000594%
BADD_D02135Tedizolid--
BADD_D02136Tedizolid phosphate--
BADD_D02150Temozolomide0.000582%
BADD_D02170Testosterone0.000227%
BADD_D02192Thalidomide0.000362%
BADD_D02214Ticagrelor0.000272%
BADD_D02247Topiramate0.000075%
BADD_D02261Tranexamic acid0.009352%
BADD_D02270Tretinoin--
BADD_D02281Trifluoperazine--
BADD_D02322Ustekinumab--
BADD_D02323Valacyclovir--
BADD_D02331Valsartan0.000079%
BADD_D02337Varenicline0.000487%
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