Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00621Desvenlafaxine--
BADD_D00622Desvenlafaxine succinate--
BADD_D00623Dexamethasone--
BADD_D00624Dexamethasone phosphate--
BADD_D00626Dexchlorpheniramine--
BADD_D00627Dexchlorpheniramine maleate--
BADD_D00628Dexlansoprazole--
BADD_D00633Dexrazoxane--
BADD_D00634Dexrazoxane hydrochloride--
BADD_D00637Dextroamphetamine sulfate--
BADD_D00638Dextromethorphan--
BADD_D00648Diazepam--
BADD_D00650Dibasic potassium phosphate--
BADD_D00652Dichlorphenamide0.015391%
BADD_D00659Dicyclomine--
BADD_D00666Diflunisal--
BADD_D00671Dihydroergotamine--
BADD_D00673Dihydrogen phosphate--
BADD_D00674Diltiazem--
BADD_D00675Diltiazem hydrochloride--
BADD_D00676Dimenhydrinate--
BADD_D00680Dimethyl fumarate0.272130%
BADD_D00686Diphenhydramine--
BADD_D00687Diphenhydramine hydrochloride--
BADD_D00692Dipyridamole--
BADD_D00693Disopyramide--
BADD_D00694Disopyramide phosphate--
BADD_D00695Disulfiram0.069869%
BADD_D00699Docetaxel--
BADD_D00701Dofetilide0.004017%
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ADReCS-Target
ADR Term Drug Name Target