Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00932Fluoxetine--
BADD_D00943Flutamide--
BADD_D00945Fluticasone--
BADD_D00946Fluticasone furoate0.000611%
BADD_D00948Fluvastatin0.005625%
BADD_D00949Fluvastatin sodium--
BADD_D00950Fluvoxamine--
BADD_D00952Folic acid--
BADD_D00957Fondaparinux sodium--
BADD_D00958Formoterol--
BADD_D00959Formoterol fumarate--
BADD_D00960Formoterol fumarate dihydrate--
BADD_D00961Fosamprenavir calcium--
BADD_D00962Fosaprepitant--
BADD_D00963Fosaprepitant dimeglumine--
BADD_D00964Foscarnet sodium--
BADD_D00965Fosfomycin--
BADD_D00967Fosinopril--
BADD_D00969Fosinoprilat--
BADD_D00976Frovatriptan--
BADD_D00977Frovatriptan succinate--
BADD_D00978Fulvestrant--
BADD_D00979Furosemide--
BADD_D00981Gabapentin--
BADD_D00982Gabapentin enacarbil--
BADD_D00983Gadobenate dimeglumine--
BADD_D00985Gadodiamide--
BADD_D00986Gadodiamide hydrate--
BADD_D00987Gadofosveset--
BADD_D00989Gadolinium--
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ADReCS-Target
ADR Term Drug Name Target