Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Headache
ADR ID BADD_A01965
ADR Hierarchy
17      Nervous system disorders
17.14      Headaches
17.14.01      Headaches NEC
17.14.01.001      Headache
Description A disorder characterized by a sensation of marked discomfort in various parts of the head, not confined to the area of distribution of any nerve. [CTCAE] The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS. [MeSH]
MedDRA Code 10019211
MeSH ID D006261; D020773
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cephalalgia | Cephalalgia or cephalgia | Cephalgia | Forehead headache | Head pain | Head throbbing | Headache | Headache (except migraine) aggravated | Headache discomfort | Headache dull | Headache fullness | Headache NOS | Headache NOS aggravated | Headache occurring | Headache temporal | Headache transient | Hemicephalgia | Hemicrania | Nocturnal headache | Pain head | Pounding in head | Temporal headache | Headache aggravated | Frontal headache | Occipital headache | Parietal headache | Headache unilateral | Drug-induced headache | Frequent headaches | Chronic headaches | Headache (excl migraine) aggravated | Throbbing headache | Intermittent headache | Retroauricular pain | Headache recurrent | Hemicephalalgia | Nuchal headache | Persistent headache | Barometric pressure headache | Nummular headache | Headaches | Head Pain | Head Pains | Pain, Head | Pains, Head | Cephalodynia | Cephalodynias | Cranial Pain | Cranial Pains | Pain, Cranial | Pains, Cranial | Cephalalgias | Cephalgias | Generalized Headache | Generalized Headaches | Headache, Generalized | Headaches, Generalized | Ocular Headache | Headache, Ocular | Headaches, Ocular | Ocular Headaches | Orthostatic Headache | Headache, Orthostatic | Headaches, Orthostatic | Orthostatic Headaches | Vertex Headache | Headache, Vertex | Headaches, Vertex | Vertex Headaches | Retro-Ocular Headache | Headache, Retro-Ocular | Headaches, Retro-Ocular | Retro Ocular Headache | Retro-Ocular Headaches | Sharp Headache | Headache, Sharp | Headaches, Sharp | Sharp Headaches | Throbbing Headache | Headache, Throbbing | Headaches, Throbbing | Throbbing Headaches | Unilateral Headache | Headache, Unilateral | Headaches, Unilateral | Unilateral Headaches | Bilateral Headache | Bilateral Headaches | Headache, Bilateral | Headaches, Bilateral | Periorbital Headache | Headache, Periorbital | Headaches, Periorbital | Periorbital Headaches
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02496Elagolix0.016934%
BADD_D02497Avatrombopag0.016553%
BADD_D02498Abemaciclib--
BADD_D02499Fostamatinib0.002949%
BADD_D02501Sarecycline0.000578%
BADD_D02503Telotristat ethyl-
BADD_D02510Rucaparib0.020248%
BADD_D02511Siponimod0.048367%
BADD_D02512Secnidazole0.000482%
BADD_D02515Pexidartinib0.002429%
BADD_D02529Atogepant0.001312%
BADD_D02530Avacopan0.001350%
BADD_D02532Belumosudil0.001230%
BADD_D02533Bempedoic acid0.000328%
BADD_D02534Berotralstat-
BADD_D02536Bremelanotide0.000435%
BADD_D02539Calcium0.004032%
BADD_D02542Cenobamate0.002665%
BADD_D02549Deucravacitinib0.003689%
BADD_D02550Diroximel fumarate0.015238%
BADD_D02552Encorafenib0.001007%
BADD_D02555Fenfluramine--
BADD_D02556Ferrous cation0.005647%
BADD_D02558Gadolinium cation (3+)-
BADD_D02563Lemborexant0.003397%
BADD_D02564Lofexidine0.001830%
BADD_D02565Lumateperone0.011342%
BADD_D02569Magnesium0.001383%
BADD_D02571Maribavir0.002540%
BADD_D02572Migalastat0.011643%
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ADReCS-Target
ADR Term Drug Name Target