Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Injection site reaction
ADR ID BADD_A02348
ADR Hierarchy
08      General disorders and administration site conditions
08.02      Administration site reactions
08.02.03      Injection site reactions
08.02.03.014      Injection site reaction
12      Injury, poisoning and procedural complications
12.07      Administration site reactions
12.07.03      Injection site reactions
12.07.03.015      Injection site reaction
Description A disorder characterized by an intense adverse reaction (usually immunologic) developing at the site of an injection. [CTCAE] Adverse reactions that occur initially at the site of injection or infusion. Milder type is confined to a local allergic flare reaction. A more severe reaction is caused by extravasation of VESICANTS from the blood vessel at the site of injection and can cause damage to the surrounding tissue. In tumor flare reaction symptoms involve well beyond the injection site such as an increase in the tumor size and tumor markers levels, bone pain, and HYPERCALCEMIA. [MeSH]
MedDRA Code 10022095
MeSH ID D000075662
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Injection site reaction | Injection site reaction NOS | Reaction injection site (NOS) | Injection site reaction (NOS) | Injection site maceration | Injection site muscle reaction | Delayed injection site reaction following multiple administrations | Injection Site Reaction | Injection Site Reactions | Injection Site Event | Injection Site Events | Injection Site Adverse Event | Infusion Site Reaction | Infusion Site Reactions | Infusion Site Adverse Reaction | Infusion Site Adverse Event
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00457Choriogonadotropin alfa--
BADD_D00463Cidofovir--
BADD_D00464Cidofovir dihydrate--
BADD_D00467Cimetidine--
BADD_D00471Ciprofloxacin--
BADD_D00472Ciprofloxacin hydrochloride--
BADD_D00475Citalopram0.000162%
BADD_D00479Cladribine--
BADD_D00483Clindamycin--
BADD_D00499Clomipramine--
BADD_D00501Clonazepam0.000303%
BADD_D00510Cloxacillin--
BADD_D00516Codeine--
BADD_D00525Collagenase clostridium histolyticum--
BADD_D00543Cyclizine--
BADD_D00544Cyclo-upup--
BADD_D00554Cyproterone--
BADD_D00555Cyproterone acetate--
BADD_D00561Cytarabine hydrochloride--
BADD_D00574Dalfampridine0.001184%
BADD_D00575Dalteparin sodium--
BADD_D00577Dantrolene sodium--
BADD_D00581Daptomycin--
BADD_D00596Deferoxamine--
BADD_D00599Degarelix--
BADD_D00600Degarelix acetate--
BADD_D00609Deoxycholic acid0.000603%
BADD_D00620Desoximetasone--
BADD_D00621Desvenlafaxine0.001515%
BADD_D00633Dexrazoxane--
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