Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Laryngospasm
ADR ID BADD_A02487
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.04      Upper respiratory tract disorders (excl infections)
22.04.02      Laryngeal spasm, oedema and obstruction
22.04.02.002      Laryngospasm
Description A disorder characterized by paroxysmal spasmodic muscular contraction of the vocal cords. [CTCAE] A disorder in which the adductor muscles of the VOCAL CORDS exhibit increased activity leading to laryngeal spasm. Laryngismus causes closure of the VOCAL FOLDS and airflow obstruction during inspiration. [MeSH]
MedDRA Code 10023891
MeSH ID D007826
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Glottic spasm | Laryngeal spasm | Laryngismus | Laryngospasm | Larynx muscle hypersensitive | Spasm glottis | Spasm larynx | Laryngospasms | Laryngeal Spasm | Laryngeal Spasms | Spasm, Laryngeal | Spasms, Laryngeal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01499Morphine sulfate--
BADD_D01506Muromonab-cd3--
BADD_D01507Mycophenolate mofetil--
BADD_D01512Nadolol--
BADD_D01515Nafcillin--
BADD_D01516Nafcillin sodium--
BADD_D01559Niacin--
BADD_D01563Nicotinate--
BADD_D01580Nitrous oxide0.000179%
BADD_D01617Ondansetron--
BADD_D01618Ondansetron hydrochloride--
BADD_D01621Optimark--
BADD_D01631Oxacillin--
BADD_D01632Oxacillin sodium--
BADD_D01633Oxaliplatin0.005708%
BADD_D01637Oxcarbazepine--
BADD_D01645Oxycodone--
BADD_D01646Oxycodone hydrochloride--
BADD_D01648Oxymorphone--
BADD_D01653Paclitaxel0.001287%
BADD_D01656Paliperidone--
BADD_D01659Palonosetron--
BADD_D01660Palonosetron hydrochloride--
BADD_D01668Pantoprazole0.000041%
BADD_D01679Paroxetine--
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
BADD_D01683Paroxetine mesylate--
BADD_D01706Penbutolol--
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