Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Malaise
ADR ID BADD_A02640
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.003      Malaise
Description A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. [CTCAE]
MedDRA Code 10025482
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Feeling sick | Feeling unwell | Felt generally ill | Felt ill | General malaise | Generally off-colour | Generally unwell | Ill feeling | Malaise | Malaise and fatigue | Sickness feeling | Stamina decreased | Unwell | Generally off-color | Post-exertional malaise | Physically unwell
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01765Phenytoin--
BADD_D01767Phosphonatoformate--
BADD_D01771Pilocarpine hydrochloride--
BADD_D01773Pimecrolimus0.000700%
BADD_D01777Pioglitazone--
BADD_D01783Pirfenidone0.030139%
BADD_D01784Piroxicam--
BADD_D01785Pitavastatin calcium--
BADD_D01788Plerixafor0.001796%
BADD_D01789Plerixafor octahydrochloride--
BADD_D01798Pomalidomide0.131045%
BADD_D01799Ponatinib--
BADD_D01803Porfimer sodium--
BADD_D01804Posaconazole--
BADD_D01807Potassium bicarbonate--
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01824Pravastatin--
BADD_D01825Pravastatin sodium--
BADD_D01826Praziquantel--
BADD_D01827Prazosin--
BADD_D01831Prednisolone--
BADD_D01832Prednisolone acetate--
BADD_D01833Prednisolone sodium phosphate--
BADD_D01834Prednisone--
BADD_D01835Pregabalin0.037670%
BADD_D01840Primidone0.001164%
BADD_D01842Procainamide--
BADD_D01843Procainamide hydrochloride--
BADD_D01848Prochlorperazine0.000536%
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