Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Malaise
ADR ID BADD_A02640
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.003      Malaise
Description A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. [CTCAE]
MedDRA Code 10025482
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Feeling sick | Feeling unwell | Felt generally ill | Felt ill | General malaise | Generally off-colour | Generally unwell | Ill feeling | Malaise | Malaise and fatigue | Sickness feeling | Stamina decreased | Unwell | Generally off-color | Post-exertional malaise | Physically unwell
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01937Rifapentine--
BADD_D01938Rifaximin--
BADD_D01942Riluzole0.003553%
BADD_D01943Rimabotulinumtoxinb--
BADD_D01948Riociguat--
BADD_D01950Risedronic acid--
BADD_D01951Risperidone--
BADD_D01952Ritonavir--
BADD_D01954Rivaroxaban--
BADD_D01955Rivastigmine0.011815%
BADD_D01956Rivastigmine tartrate--
BADD_D01957Rizatriptan0.000914%
BADD_D01962Roflumilast0.018625%
BADD_D01963Rolapitant0.000259%
BADD_D01964Romidepsin0.000112%
BADD_D01966Ropinirole0.000309%
BADD_D01968Ropivacaine hydrochloride--
BADD_D01969Ropivacaine hydrochloride monohydrate--
BADD_D01971Rosuvastatin0.000664%
BADD_D01973Rotigotine0.005797%
BADD_D01974Rotigotine hydrochloride--
BADD_D01975Roxithromycin--
BADD_D01978Ruxolitinib0.020791%
BADD_D01981Salmeterol0.007178%
BADD_D01987Sapropterin0.051317%
BADD_D01989Saquinavir mesylate--
BADD_D01990Sargramostim--
BADD_D01994Scopolamine0.002696%
BADD_D02002Selegiline--
BADD_D02003Selegiline hydrochloride--
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