Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Malaise
ADR ID BADD_A02640
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.003      Malaise
Description A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. [CTCAE]
MedDRA Code 10025482
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Feeling sick | Feeling unwell | Felt generally ill | Felt ill | General malaise | Generally off-colour | Generally unwell | Ill feeling | Malaise | Malaise and fatigue | Sickness feeling | Stamina decreased | Unwell | Generally off-color | Post-exertional malaise | Physically unwell
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02006Selexipag0.004976%
BADD_D02007Semaxanib--
BADD_D02010Sertraline--
BADD_D02011Sertraline hydrochloride--
BADD_D02016Sibutramine--
BADD_D02018Sildenafil0.009427%
BADD_D02026Simvastatin0.000310%
BADD_D02028Sirolimus--
BADD_D02029Sitagliptin--
BADD_D02031Sitaxentan--
BADD_D02033Sodium aurothiomalate--
BADD_D02034Sodium bicarbonate0.000854%
BADD_D02038Sodium ferric gluconate complex-
BADD_D02039Sodium fluoride--
BADD_D02047Sodium oxybate0.063842%
BADD_D02055Somatropin--
BADD_D02056Somatuline depot--
BADD_D02058Sorafenib0.008104%
BADD_D02060Sotalol0.001968%
BADD_D02062Sparfloxacin--
BADD_D02066Spironolactone--
BADD_D02070Streptokinase--
BADD_D02076Strontium ranelate--
BADD_D02081Sucralfate0.000255%
BADD_D02091Sulfamethoxazole--
BADD_D02093Sulfasalazine0.009608%
BADD_D02097Sulindac--
BADD_D02098Sumatriptan0.000206%
BADD_D02099Sumatriptan succinate--
BADD_D02100Sunitinib0.021591%
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