Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Myocardial ischaemia
ADR ID BADD_A02936
ADR Hierarchy
02      Cardiac disorders
02.02      Coronary artery disorders
02.02.02      Ischaemic coronary artery disorders
02.02.02.008      Myocardial ischaemia
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.04      Coronary necrosis and vascular insufficiency
24.04.04.010      Myocardial ischaemia
Description A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION). [MeSH]
MedDRA Code 10028600
MeSH ID D017202
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cardiac ischaemia | Chronic ischaemic heart disease, unspecified | Chronic ischemic heart disease, unspecified | IHD | Ischaemic heart disease | Ischemia coronary artery origin | Ischemia myocardial | Myocardial ischaemia | Myocardial ischemia | Other acute and subacute forms of ischaemic heart disease | Other acute and subacute forms of ischemic heart disease | Other forms of chronic ischaemic heart disease | Other forms of chronic ischaemic heart disease, other | Other forms of chronic ischemic heart disease | Other specified acute and subacute form of ischemic heart disease | Other specified acute and subacute forms of ischemic heart disease | Other specified forms of chronic ischaemic heart disease | Other specified forms of chronic ischemic heart disease | Silent myocardial ischaemia | Silent myocardial ischemia | Ischemic heart disease | Cardiac ischemia | Ischaemia coronary artery origin | Ischaemia myocardial | Refractory cardiac ischemia | Refractory cardiac ischaemia | Acute heart ischemia | Acute myocardial ischemia | Acute myocardial ischaemia | Myocardial ischaemia recurrent | Acute heart ischaemia | Myocardial ischemia recurrent | Demand ischemia | Demand ischaemia | Exercise induced myocardial ischemia | Exercise induced myocardial ischaemia | Myocardial Ischemia | Ischemia, Myocardial | Ischemias, Myocardial | Myocardial Ischemias | Ischemic Heart Disease | Heart Disease, Ischemic | Disease, Ischemic Heart | Diseases, Ischemic Heart | Heart Diseases, Ischemic | Ischemic Heart Diseases
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00931Fluorouracil0.000551%
BADD_D00976Frovatriptan--
BADD_D00977Frovatriptan succinate--
BADD_D00979Furosemide0.000056%
BADD_D00981Gabapentin0.000063%
BADD_D00982Gabapentin enacarbil-
BADD_D00983Gadobenate dimeglumine--
BADD_D00986Gadodiamide hydrate--
BADD_D00987Gadofosveset--
BADD_D00996Galantamine--
BADD_D00997Galantamine hydrobromide--
BADD_D01083Hydrochlorothiazide0.000020%
BADD_D01110Hydroxyurea0.000168%
BADD_D01117Ibandronic acid--
BADD_D01119Ibrutinib0.000392%
BADD_D01136Imatinib0.000839%
BADD_D01147Indacaterol--
BADD_D01167Interferon alfa-2b--
BADD_D01178Iodixanol--
BADD_D01180Iohexol--
BADD_D01181Iopamidol--
BADD_D01182Iopromide--
BADD_D01186Ioversol--
BADD_D01188Ioxaglic acid--
BADD_D01195Irinotecan--
BADD_D01196Irinotecan hydrochloride--
BADD_D01210Isosorbide dinitrate0.003573%
BADD_D01222Ixabepilone--
BADD_D01252Leflunomide0.000643%
BADD_D01253Lenalidomide--
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ADReCS-Target
ADR Term Drug Name Target