Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Peripheral motor neuropathy
ADR ID BADD_A03368
ADR Hierarchy
17      Nervous system disorders
17.09      Peripheral neuropathies
17.09.03      Peripheral neuropathies NEC
17.09.03.004      Peripheral motor neuropathy
Description A disorder characterized by damage or dysfunction of the peripheral motor nerves. [CTCAE] Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance. [MeSH]
MedDRA Code 10034580
MeSH ID D011115
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Motor peripheral neuropathy | Neuritis motor | Peripheral motor neuropathy | Motor polyneuropathy | Motor polyneuropathy axonal | Polyneuropathies | Polyneuropathy | Polyneuropathy, Motor | Motor Polyneuropathies | Motor Polyneuropathy | Polyneuropathies, Motor | Polyneuropathy, Familial | Familial Polyneuropathies | Familial Polyneuropathy | Polyneuropathies, Familial | Polyneuropathy, Inherited | Inherited Polyneuropathies | Inherited Polyneuropathy | Polyneuropathies, Inherited | Polyneuropathy, Acquired | Acquired Polyneuropathies | Acquired Polyneuropathy | Polyneuropathies, Acquired | Polyneuropathy, Critical Illness | Critical Illness Polyneuropathies | Critical Illness Polyneuropathy | Polyneuropathies, Critical Illness
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00194Azacitidine0.000112%
BADD_D00284Bortezomib0.000280%
BADD_D00291Brentuximab vedotin--
BADD_D00349Capecitabine0.000112%
BADD_D00364Carboplatin0.000336%
BADD_D00367Carfilzomib--
BADD_D00414Ceritinib--
BADD_D00429Chlorambucil--
BADD_D00479Cladribine--
BADD_D00518Colchicine--
BADD_D00560Cytarabine--
BADD_D00571Dactinomycin0.000112%
BADD_D00699Docetaxel--
BADD_D00723Doxorubicin0.000112%
BADD_D00798Eribulin0.000246%
BADD_D00931Fluorouracil0.000184%
BADD_D01009Gemcitabine--
BADD_D01010Gemcitabine hydrochloride--
BADD_D01136Imatinib0.000168%
BADD_D01222Ixabepilone--
BADD_D01253Lenalidomide--
BADD_D01369Mefloquine--
BADD_D01401Metformin0.000005%
BADD_D01449Metronidazole0.000039%
BADD_D01549Nelarabine--
BADD_D01580Nitrous oxide0.000804%
BADD_D01633Oxaliplatin0.000392%
BADD_D01653Paclitaxel0.000526%
BADD_D01701Pemetrexed--
BADD_D01702Pemetrexed disodium--
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