Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Respiratory failure
ADR ID BADD_A03813
ADR Hierarchy
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.04      Respiratory acidoses
14.01.04.003      Respiratory failure
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.06      Respiratory failures (excl neonatal)
22.02.06.002      Respiratory failure
Description A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. [CTCAE] Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) [MeSH]
MedDRA Code 10038695
MeSH ID D012131
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Failure respiratory | Other pulmonary insufficiency, not elsewhere classified | Pulmonary insufficiency following trauma and surgery | Respiration failure | Respiratory failure | Respiratory failure (excl neonatal) | Respiratory insufficiency | Ventilatory failure | Pulmonary failure | Hypercapnic respiratory failure | Restrictive respiratory insufficiency | Respiratory failure aggravated | Hypoxic respiratory failure | End stage lung disease | Respiratory failure type 1 | Respiratory failure type 2 | Hypoxemic respiratory failure | Hypoxaemic respiratory failure | Respiratory Insufficiency | Respiratory Failure | Respiratory Depression | Ventilatory Depression | Depressions, Ventilatory
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01804Posaconazole0.018913%
BADD_D01817Pramipexole0.000478%
BADD_D01818Pramipexole dihydrochloride--
BADD_D01822Prasugrel0.000384%
BADD_D01831Prednisolone0.001311%
BADD_D01834Prednisone0.000327%
BADD_D01835Pregabalin--
BADD_D01836Prilocaine--
BADD_D01854Promethazine0.000038%
BADD_D01856Propafenone0.000418%
BADD_D01858Propagermanium--
BADD_D01864Propofol0.001697%
BADD_D01867Propranolol0.000588%
BADD_D01869Propylthiouracil0.018808%
BADD_D01881Pyridostigmine0.012750%
BADD_D01888Quetiapine0.000491%
BADD_D01898Rabeprazole--
BADD_D01905Raltegravir0.002472%
BADD_D01909Ramipril0.000746%
BADD_D01915Ranolazine0.001138%
BADD_D01917Rasburicase--
BADD_D01919Reboxetine--
BADD_D01933Ribavirin--
BADD_D01935Rifabutin0.014583%
BADD_D01942Riluzole0.000808%
BADD_D01948Riociguat0.001685%
BADD_D01952Ritonavir--
BADD_D01955Rivastigmine0.001626%
BADD_D01956Rivastigmine tartrate--
BADD_D01959Rocuronium--
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