Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Respiratory failure
ADR ID BADD_A03813
ADR Hierarchy
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.04      Respiratory acidoses
14.01.04.003      Respiratory failure
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.06      Respiratory failures (excl neonatal)
22.02.06.002      Respiratory failure
Description A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. [CTCAE] Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) [MeSH]
MedDRA Code 10038695
MeSH ID D012131
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Failure respiratory | Other pulmonary insufficiency, not elsewhere classified | Pulmonary insufficiency following trauma and surgery | Respiration failure | Respiratory failure | Respiratory failure (excl neonatal) | Respiratory insufficiency | Ventilatory failure | Pulmonary failure | Hypercapnic respiratory failure | Restrictive respiratory insufficiency | Respiratory failure aggravated | Hypoxic respiratory failure | End stage lung disease | Respiratory failure type 1 | Respiratory failure type 2 | Hypoxemic respiratory failure | Hypoxaemic respiratory failure | Respiratory Insufficiency | Respiratory Failure | Respiratory Depression | Ventilatory Depression | Depressions, Ventilatory
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02373Warfarin0.001029%
BADD_D02380Zanamivir0.001129%
BADD_D02392Zoledronic acid0.027198%
BADD_D02396Zonisamide0.001450%
BADD_D02412Octreotide--
BADD_D02415Ziprasidone0.000816%
BADD_D02421Foscarnet0.000282%
BADD_D02428Loperamide0.000507%
BADD_D02442Magnesium oxide0.000182%
BADD_D02443Tiotropium0.001236%
BADD_D02452Icatibant--
BADD_D02453Midostaurin0.000224%
BADD_D02467Naloxegol0.000439%
BADD_D02470Nintedanib0.005955%
BADD_D02471Oxygen0.010532%
BADD_D02473Sodium chloride0.000845%
BADD_D02480Alectinib0.000336%
BADD_D02487Baricitinib0.002942%
BADD_D02493Selinexor0.000168%
BADD_D02502Letermovir0.000423%
BADD_D02504Lorlatinib0.000560%
BADD_D02505Gilteritinib0.000168%
BADD_D02508Edaravone0.002692%
BADD_D02526Larotrectinib0.000112%
BADD_D02528Asciminib0.000112%
BADD_D02540Capmatinib0.000392%
BADD_D02566Lurbinectedin0.000112%
BADD_D02569Magnesium0.000589%
BADD_D02573Mobocertinib0.000168%
BADD_D02574Molnupiravir0.000988%
The 13th Page    First    Pre   13 14    Next   Last    Total 14 Pages