Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Respiratory failure
ADR ID BADD_A03813
ADR Hierarchy
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.04      Respiratory acidoses
14.01.04.003      Respiratory failure
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.06      Respiratory failures (excl neonatal)
22.02.06.002      Respiratory failure
Description A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. [CTCAE] Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) [MeSH]
MedDRA Code 10038695
MeSH ID D012131
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Failure respiratory | Other pulmonary insufficiency, not elsewhere classified | Pulmonary insufficiency following trauma and surgery | Respiration failure | Respiratory failure | Respiratory failure (excl neonatal) | Respiratory insufficiency | Ventilatory failure | Pulmonary failure | Hypercapnic respiratory failure | Restrictive respiratory insufficiency | Respiratory failure aggravated | Hypoxic respiratory failure | End stage lung disease | Respiratory failure type 1 | Respiratory failure type 2 | Hypoxemic respiratory failure | Hypoxaemic respiratory failure | Respiratory Insufficiency | Respiratory Failure | Respiratory Depression | Ventilatory Depression | Depressions, Ventilatory
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00947Fluticasone propionate--
BADD_D00964Foscarnet sodium--
BADD_D00979Furosemide0.000146%
BADD_D00981Gabapentin--
BADD_D00983Gadobenate dimeglumine--
BADD_D01001Galsulfase--
BADD_D01008Gefitinib0.000616%
BADD_D01009Gemcitabine0.000672%
BADD_D01010Gemcitabine hydrochloride--
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01081Hydralazine0.000729%
BADD_D01086Hydrocortisone0.000092%
BADD_D01096Hydromorphone--
BADD_D01103Hydroxychloroquine0.012086%
BADD_D01110Hydroxyurea0.000448%
BADD_D01119Ibrutinib0.005429%
BADD_D01120Ibuprofen0.000013%
BADD_D01121Ibuprofen lysine--
BADD_D01130Idelalisib0.000951%
BADD_D01133Ifosfamide0.000280%
BADD_D01135Iloprost0.001398%
BADD_D01136Imatinib0.001791%
BADD_D01143Immune globulin--
BADD_D01150Indinavir--
BADD_D01167Interferon alfa-2b--
BADD_D01178Iodixanol0.024897%
BADD_D01181Iopamidol0.014227%
BADD_D01182Iopromide0.028454%
BADD_D01186Ioversol0.021340%
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