Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Respiratory failure
ADR ID BADD_A03813
ADR Hierarchy
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.04      Respiratory acidoses
14.01.04.003      Respiratory failure
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.06      Respiratory failures (excl neonatal)
22.02.06.002      Respiratory failure
Description A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. [CTCAE] Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) [MeSH]
MedDRA Code 10038695
MeSH ID D012131
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Failure respiratory | Other pulmonary insufficiency, not elsewhere classified | Pulmonary insufficiency following trauma and surgery | Respiration failure | Respiratory failure | Respiratory failure (excl neonatal) | Respiratory insufficiency | Ventilatory failure | Pulmonary failure | Hypercapnic respiratory failure | Restrictive respiratory insufficiency | Respiratory failure aggravated | Hypoxic respiratory failure | End stage lung disease | Respiratory failure type 1 | Respiratory failure type 2 | Hypoxemic respiratory failure | Hypoxaemic respiratory failure | Respiratory Insufficiency | Respiratory Failure | Respiratory Depression | Ventilatory Depression | Depressions, Ventilatory
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01599Olanzapine0.002842%
BADD_D01616Onabotulinumtoxina--
BADD_D01617Ondansetron0.000064%
BADD_D01629Osimertinib0.002071%
BADD_D01633Oxaliplatin0.002406%
BADD_D01636Oxazepam0.001520%
BADD_D01645Oxycodone--
BADD_D01653Paclitaxel0.003134%
BADD_D01659Palonosetron--
BADD_D01665Pancuronium bromide--
BADD_D01667Panobinostat lactate--
BADD_D01668Pantoprazole0.000114%
BADD_D01674Parecoxib--
BADD_D01676Paricalcitol0.027469%
BADD_D01687Pazopanib0.001567%
BADD_D01693Pegfilgrastim--
BADD_D01701Pemetrexed0.000448%
BADD_D01726Pentobarbital--
BADD_D01735Pergolide--
BADD_D01752Phenobarbital0.000325%
BADD_D01756Phentermine0.000109%
BADD_D01765Phenytoin0.002008%
BADD_D01767Phosphonatoformate--
BADD_D01771Pilocarpine hydrochloride0.001486%
BADD_D01783Pirfenidone0.012345%
BADD_D01788Plerixafor0.001796%
BADD_D01798Pomalidomide--
BADD_D01799Ponatinib0.000560%
BADD_D01802Porfimer--
BADD_D01803Porfimer sodium--
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