Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Restlessness
ADR ID BADD_A03825
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.05      Neurological signs and symptoms NEC
17.02.05.021      Restlessness
19      Psychiatric disorders
19.11      Changes in physical activity
19.11.02      Increased physical activity levels
19.11.02.002      Restlessness
Description A disorder characterized by an inability to rest, relax or be still. [CTCAE] A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions. [MeSH]
MedDRA Code 10038743
MeSH ID D011595
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Marked restlessness | Muscular unrest | Physically restless | Restless | Restlessness | Restlessness (drug related) | Restlessness (phenothiazine) | Restlessness marked | Unrest | Restlessness aggravated | Inner restlessness | Psychomotor Agitation | Psychomotor Hyperactivity | Hyperactivity, Psychomotor | Psychomotor Restlessness | Restlessness, Psychomotor | Agitation, Psychomotor | Excitement, Psychomotor | Psychomotor Excitement | Akathisia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01897Quinine sulfate--
BADD_D01909Ramipril0.000280%
BADD_D01933Ribavirin--
BADD_D01951Risperidone0.004922%
BADD_D01955Rivastigmine0.001626%
BADD_D01956Rivastigmine tartrate--
BADD_D01957Rizatriptan0.000273%
BADD_D01962Roflumilast0.006383%
BADD_D01973Rotigotine0.001651%
BADD_D01994Scopolamine0.000972%
BADD_D01997Secobarbital--
BADD_D02003Selegiline hydrochloride--
BADD_D02010Sertraline0.000599%
BADD_D02026Simvastatin0.000068%
BADD_D02046Sodium nitroprusside--
BADD_D02047Sodium oxybate0.013895%
BADD_D02053Sofosbuvir0.002427%
BADD_D02066Spironolactone--
BADD_D02084Sugammadex--
BADD_D02103Suvorexant0.001620%
BADD_D02104Tacrine hydrochloride--
BADD_D02115Tapentadol0.002357%
BADD_D02116Tapentadol hydrochloride--
BADD_D02118Tasimelteon0.000666%
BADD_D02139Tegaserod maleate--
BADD_D02147Telmisartan0.000651%
BADD_D02148Temazepam0.000263%
BADD_D02160Terbinafine0.000447%
BADD_D02174Testosterone undecanoate--
BADD_D02175Tetrabenazine0.004199%
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