Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Scleroderma
ADR ID BADD_A03938
ADR Hierarchy
10      Immune system disorders
10.04      Autoimmune disorders
10.04.07      Scleroderma and associated disorders
10.04.07.001      Scleroderma
15      Musculoskeletal and connective tissue disorders
15.06      Connective tissue disorders (excl congenital)
15.06.01      Connective tissue disorders NEC
15.06.01.002      Scleroderma
23      Skin and subcutaneous tissue disorders
23.03      Epidermal and dermal conditions
23.03.02      Connective tissue disorders
23.03.02.005      Scleroderma
Description A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules. [MeSH]
MedDRA Code 10039710
MeSH ID D012594
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Dermatosclerosis | Scleroderma | Scleroderma, Localized | Localized Scleroderma | Sclerodermas, Localized | Scleroderma, Circumscribed | Circumscribed Scleroderma | Morphea | Morpheas | Scleroderma, Linear | Linear Scleroderma | Frontal Linear Scleroderma en Coup de Sabre
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00036Acitretin--
BADD_D00100Ambrisentan0.002768%
BADD_D00277Bisoprolol--
BADD_D00280Bleomycin--
BADD_D00281Bleomycin sulfate--
BADD_D00285Bosentan0.003598%
BADD_D00349Capecitabine0.000112%
BADD_D00364Carboplatin0.000112%
BADD_D00424Cevimeline--
BADD_D00425Cevimeline hydrochloride--
BADD_D00465Cilazapril monohydrate--
BADD_D00549Cyclophosphamide--
BADD_D00551Cyclosporine0.000221%
BADD_D00555Cyproterone acetate--
BADD_D00589Dasatinib0.000168%
BADD_D00699Docetaxel--
BADD_D00788Epoprostenol0.000247%
BADD_D00858Everolimus0.000153%
BADD_D00861Exemestane0.001046%
BADD_D01110Hydroxyurea0.000112%
BADD_D01119Ibrutinib0.000224%
BADD_D01135Iloprost0.000288%
BADD_D01136Imatinib0.000280%
BADD_D01194Irbesartan0.000441%
BADD_D01257Letrozole0.000263%
BADD_D01281Levonorgestrel0.000946%
BADD_D01336Macitentan0.002551%
BADD_D01365Medroxyprogesterone--
BADD_D01366Medroxyprogesterone acetate--
BADD_D01507Mycophenolate mofetil--
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