Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Ventricular fibrillation
ADR ID BADD_A04561
ADR Hierarchy
02      Cardiac disorders
02.03      Cardiac arrhythmias
02.03.04      Ventricular arrhythmias and cardiac arrest
02.03.04.008      Ventricular fibrillation
Description A disorder characterized by a dysrhythmia without discernible QRS complexes due to rapid repetitive excitation of myocardial fibers without coordinated contraction of the ventricles. [CTCAE] A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST. [MeSH]
MedDRA Code 10047290
MeSH ID D014693
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Fibrillation paroxysmal vent | Fibrillation ventricular | Paroxysmal ventricular fibrillation | Ventricular fibrillation | Ventricular fibrillation and flutter | Ventricular fibrillation paroxysm | Ventricular fibrillation paroxysmal | VF | Recurrent ventricular fibrillation | Ventricular Fibrillation | Fibrillation, Ventricular | Fibrillations, Ventricular | Ventricular Fibrillations
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01656Paliperidone--
BADD_D01679Paroxetine--
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
BADD_D01683Paroxetine mesylate--
BADD_D01701Pemetrexed0.000112%
BADD_D01734Perflutren-
BADD_D01765Phenytoin--
BADD_D01774Pimozide--
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01822Prasugrel0.000384%
BADD_D01826Praziquantel--
BADD_D01831Prednisolone0.000140%
BADD_D01835Pregabalin--
BADD_D01842Procainamide--
BADD_D01856Propafenone0.000418%
BADD_D01864Propofol0.000625%
BADD_D01867Propranolol0.000240%
BADD_D01886Pyrimethamine0.000142%
BADD_D01888Quetiapine0.000082%
BADD_D01895Quinine--
BADD_D01896Quinine dihydrochloride--
BADD_D01897Quinine sulfate--
BADD_D01909Ramipril0.000186%
BADD_D01915Ranolazine0.000996%
BADD_D01916Rasagiline mesylate--
BADD_D01920Refludan--
BADD_D01923Remifentanil hydrochloride--
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ADReCS-Target
ADR Term Drug Name Target