Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Ventricular fibrillation
ADR ID BADD_A04561
ADR Hierarchy
02      Cardiac disorders
02.03      Cardiac arrhythmias
02.03.04      Ventricular arrhythmias and cardiac arrest
02.03.04.008      Ventricular fibrillation
Description A disorder characterized by a dysrhythmia without discernible QRS complexes due to rapid repetitive excitation of myocardial fibers without coordinated contraction of the ventricles. [CTCAE] A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST. [MeSH]
MedDRA Code 10047290
MeSH ID D014693
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Fibrillation paroxysmal vent | Fibrillation ventricular | Paroxysmal ventricular fibrillation | Ventricular fibrillation | Ventricular fibrillation and flutter | Ventricular fibrillation paroxysm | Ventricular fibrillation paroxysmal | VF | Recurrent ventricular fibrillation | Ventricular Fibrillation | Fibrillation, Ventricular | Fibrillations, Ventricular | Ventricular Fibrillations
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01942Riluzole--
BADD_D01951Risperidone0.000485%
BADD_D01957Rizatriptan--
BADD_D01961Rofecoxib--
BADD_D01968Ropivacaine hydrochloride--
BADD_D01971Rosuvastatin0.000026%
BADD_D02010Sertraline0.000070%
BADD_D02015Sevoflurane0.000357%
BADD_D02016Sibutramine--
BADD_D02017Sibutramine hydrochloride--
BADD_D02018Sildenafil0.000322%
BADD_D02029Sitagliptin0.000080%
BADD_D02060Sotalol0.001546%
BADD_D02070Streptokinase--
BADD_D02079Succinylcholine--
BADD_D02084Sugammadex0.001859%
BADD_D02098Sumatriptan0.000056%
BADD_D02105Tacrolimus--
BADD_D02106Tadalafil0.000293%
BADD_D02147Telmisartan0.000390%
BADD_D02167Terlipressin--
BADD_D02170Testosterone0.000500%
BADD_D02214Ticagrelor0.000952%
BADD_D02230Tizanidine--
BADD_D02246Tolvaptan0.000087%
BADD_D02261Tranexamic acid0.007794%
BADD_D02270Tretinoin0.000107%
BADD_D02325Valdecoxib--
BADD_D02346Venlafaxine0.000048%
BADD_D02347Venlafaxine hydrochloride--
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ADReCS-Target
ADR Term Drug Name Target