Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Acute kidney injury
ADR ID BADD_A06560
ADR Hierarchy
20      Renal and urinary disorders
20.01      Renal disorders (excl nephropathies)
20.01.03      Renal failure and impairment
20.01.03.016      Acute kidney injury
Description A disorder characterized by the acute loss of renal function (within 2 weeks) and is traditionally classified as pre-renal (low blood flow into kidney), renal (kidney damage) and post-renal causes (ureteral or bladder outflow obstruction). [CTCAE] Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. | Conditions in which the function of KIDNEYS deteriorates suddenly in a matter of days or even hours. It is characterized by the sudden drop in GLOMERULAR FILTRATION RATE. [MeSH]
MedDRA Code 10069339
MeSH ID D058186
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acute kidney failure | Acute on chronic renal failure | Acute prerenal failure | Acute renal failure | Acute renal failure following labor and delivery | Acute renal failure following labor and delivery, postpartum condition or complication | Acute renal failure following labor and delivery, unspecified as to episode of care | Acute renal failure following labour and delivery | Acute renal failure with delivery, with mention of postpartum complication | Acute renal failure with lesion of renal cortical necrosis | Acute renal failure with lesion of renal medullary (papillary) necrosis | Acute renal failure with lesion of tubular necrosis | Acute renal failure with other specified pathological lesion in kidney | Acute renal failure, unspecified | ARF | Azotemia prerenal | Failure kidney acute | Kidney failure acute | Renal failure acute | Renal failure acute hypotensive | Renal failure acute ischaemic | Renal failure acute ischemic | Renal failure acute on chronic | Renal failure acute uratic | Renal shutdown acute | Shutdown renal | Acute renal insufficiency | Rhabdomyolysis-induced renal failure | Azotaemia prerenal | Acute oliguric renal failure | Acute kidney injury | Stage 1 acute kidney injury | Stage 2 acute kidney injury | Stage 3 acute kidney injury | Acute nonoliguric renal failure | Acute prerenal insufficiency | Acute Kidney Injury | Acute Kidney Injuries | Kidney Injuries, Acute | Kidney Injury, Acute | Acute Renal Injury | Acute Renal Injuries | Renal Injuries, Acute | Renal Injury, Acute | Renal Insufficiency, Acute | Acute Renal Insufficiencies | Renal Insufficiencies, Acute | Acute Renal Insufficiency | Kidney Insufficiency, Acute | Acute Kidney Insufficiencies | Kidney Insufficiencies, Acute | Acute Kidney Insufficiency | Kidney Failure, Acute | Acute Kidney Failures | Kidney Failures, Acute | Acute Renal Failure | Acute Renal Failures | Renal Failures, Acute | Renal Failure, Acute | Acute Kidney Failure
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02334Vandetanib0.000280%
BADD_D02337Varenicline--
BADD_D02344Vemurafenib0.003492%
BADD_D02348Verapamil0.000643%
BADD_D02363Vinorelbine0.000168%
BADD_D02367Voltaren--
BADD_D02369Voriconazole--
BADD_D02370Vorinostat0.000112%
BADD_D02373Warfarin0.001767%
BADD_D02375Water0.042171%
BADD_D02378Zalcitabine--
BADD_D02380Zanamivir0.000847%
BADD_D02381Ziconotide--
BADD_D02382Ziconotide acetate--
BADD_D02383Zidovudine0.011051%
BADD_D02389Ziprasidone hydrochloride--
BADD_D02392Zoledronic acid0.122247%
BADD_D02393Zolmitriptan0.001692%
BADD_D02394Zolpidem--
BADD_D02395Zolpidem tartrate--
BADD_D02418Doxylamine0.012073%
BADD_D02421Foscarnet0.001694%
BADD_D02423Fondaparinux0.014802%
BADD_D02428Loperamide0.000845%
BADD_D02441Rasagiline0.005683%
BADD_D02442Magnesium oxide0.001824%
BADD_D02460Ganirelix0.000279%
BADD_D02469Edoxaban0.000206%
BADD_D02470Nintedanib--
BADD_D02471Oxygen0.002478%
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