Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Acute kidney injury
ADR ID BADD_A06560
ADR Hierarchy
20      Renal and urinary disorders
20.01      Renal disorders (excl nephropathies)
20.01.03      Renal failure and impairment
20.01.03.016      Acute kidney injury
Description A disorder characterized by the acute loss of renal function (within 2 weeks) and is traditionally classified as pre-renal (low blood flow into kidney), renal (kidney damage) and post-renal causes (ureteral or bladder outflow obstruction). [CTCAE] Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. | Conditions in which the function of KIDNEYS deteriorates suddenly in a matter of days or even hours. It is characterized by the sudden drop in GLOMERULAR FILTRATION RATE. [MeSH]
MedDRA Code 10069339
MeSH ID D058186
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acute kidney failure | Acute on chronic renal failure | Acute prerenal failure | Acute renal failure | Acute renal failure following labor and delivery | Acute renal failure following labor and delivery, postpartum condition or complication | Acute renal failure following labor and delivery, unspecified as to episode of care | Acute renal failure following labour and delivery | Acute renal failure with delivery, with mention of postpartum complication | Acute renal failure with lesion of renal cortical necrosis | Acute renal failure with lesion of renal medullary (papillary) necrosis | Acute renal failure with lesion of tubular necrosis | Acute renal failure with other specified pathological lesion in kidney | Acute renal failure, unspecified | ARF | Azotemia prerenal | Failure kidney acute | Kidney failure acute | Renal failure acute | Renal failure acute hypotensive | Renal failure acute ischaemic | Renal failure acute ischemic | Renal failure acute on chronic | Renal failure acute uratic | Renal shutdown acute | Shutdown renal | Acute renal insufficiency | Rhabdomyolysis-induced renal failure | Azotaemia prerenal | Acute oliguric renal failure | Acute kidney injury | Stage 1 acute kidney injury | Stage 2 acute kidney injury | Stage 3 acute kidney injury | Acute nonoliguric renal failure | Acute prerenal insufficiency | Acute Kidney Injury | Acute Kidney Injuries | Kidney Injuries, Acute | Kidney Injury, Acute | Acute Renal Injury | Acute Renal Injuries | Renal Injuries, Acute | Renal Injury, Acute | Renal Insufficiency, Acute | Acute Renal Insufficiencies | Renal Insufficiencies, Acute | Acute Renal Insufficiency | Kidney Insufficiency, Acute | Acute Kidney Insufficiencies | Kidney Insufficiencies, Acute | Acute Kidney Insufficiency | Kidney Failure, Acute | Acute Kidney Failures | Kidney Failures, Acute | Acute Renal Failure | Acute Renal Failures | Renal Failures, Acute | Renal Failure, Acute | Acute Kidney Failure
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02472Sonidegib0.000224%
BADD_D02480Alectinib0.000672%
BADD_D02487Baricitinib0.001808%
BADD_D02489Neratinib--
BADD_D02506Erdafitinib0.000224%
BADD_D02508Edaravone0.002423%
BADD_D02533Bempedoic acid0.000021%
BADD_D02539Calcium0.001370%
BADD_D02541Cefiderocol0.000073%
BADD_D02544Copanlisib0.000112%
BADD_D02545Dacomitinib0.000112%
BADD_D02552Encorafenib--
BADD_D02553Entrectinib0.000280%
BADD_D02554Fedratinib0.000224%
BADD_D02556Ferrous cation0.001882%
BADD_D02557Finerenone0.000407%
BADD_D02559Glasdegib0.000112%
BADD_D02560Iomeprol0.010670%
BADD_D02566Lurbinectedin0.000112%
BADD_D02569Magnesium0.000589%
BADD_D02573Mobocertinib0.000168%
BADD_D02577Oseltamivir acid0.002726%
BADD_D02588Remdesivir0.026673%
BADD_D02593Selpercatinib0.000112%
BADD_D02599Tepotinib0.000168%
BADD_D02609Zanubrutinib0.000224%
BADD_D02617Cephalothin--
BADD_D02626Methoxyflurane--
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