Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cisplatin
Drug ID BADD_D00474
Description Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.
Indications and Usage For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.
Marketing Status approved
ATC Code L01XA01
DrugBank ID DB00515
KEGG ID D00275
MeSH ID D002945
PubChem ID 5702198
TTD Drug ID D0U5HU
NDC Product Code 16729-288; 25021-253; 0143-9505; 68554-0077; 0143-9504; 68001-283; 44567-509; 50711-0001; 44567-510; 63323-103; 0703-5747; 0703-5748; 44567-530; 60505-6277; 68083-163; 44567-511; 49452-2078; 54875-0001; 67184-0010; 68083-162; 70860-206; 49812-0009; 72659-864
UNII Q20Q21Q62J
Synonyms Cisplatin | cis-Diamminedichloroplatinum(II) | Platinum Diamminodichloride | Diamminodichloride, Platinum | cis-Platinum | cis Platinum | Dichlorodiammineplatinum | cis-Diamminedichloroplatinum | cis Diamminedichloroplatinum | cis-Dichlorodiammineplatinum(II) | NSC-119875 | Platino | Platinol | Biocisplatinum | Platidiam
Chemical Information
Molecular Formula PtCl2(NH3)2
CAS Registry Number 15663-27-1
SMILES N.N.Cl[Pt]Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pericarditis02.06.02.0010.000112%
Peripheral ischaemia24.04.03.0020.000504%
Peripheral sensory neuropathy17.09.03.0050.000392%
Peroneal nerve palsy17.09.02.0030.000112%Not Available
Petechiae23.06.01.003; 01.01.03.002; 24.07.06.0040.000112%Not Available
Pharyngeal haemorrhage24.07.02.017; 22.04.05.0020.000112%
Pharyngeal ulceration22.04.05.0040.000246%Not Available
Phlebitis24.12.03.004; 12.02.01.0020.000437%
Pleural effusion22.05.02.0020.001511%
Pneumonitis22.01.01.0060.000783%
Pneumothorax22.05.02.0030.000302%
Pollakiuria20.02.02.0070.000224%
Polyneuropathy17.09.03.0120.000168%Not Available
Polyuria20.02.03.0020.000168%Not Available
Portal hypertension24.08.06.001; 09.01.06.0060.000168%
Portal vein thrombosis24.01.03.003; 09.01.06.0070.000112%
Presyncope02.11.04.013; 24.06.02.010; 17.02.05.0090.000392%
Proctalgia07.03.02.0010.000112%
Proctitis07.08.04.0010.000224%
Productive cough22.02.03.0050.002004%
Pulmonary alveolar haemorrhage22.01.02.005; 24.07.01.0150.000280%Not Available
Pulmonary congestion24.03.08.001; 22.01.03.002; 02.05.02.0020.000280%Not Available
Pulmonary embolism24.01.06.001; 22.06.02.0010.003996%Not Available
Pulmonary fibrosis22.01.02.0060.000168%
Pulmonary haemorrhage24.07.01.016; 22.12.01.0090.000112%
Pulmonary oedema22.01.03.003; 02.05.02.0030.000504%
Pulmonary thrombosis22.06.02.003; 24.01.06.0020.000112%Not Available
Pyrexia08.05.02.0030.009592%
Rash23.03.13.001--Not Available
Rash macular23.03.13.003--Not Available
The 10th Page    First    Pre   10 11 12 13 14    Next   Last    Total 20 Pages
ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene