Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mexiletine
Drug ID BADD_D01452
Description Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Indications and Usage For the treatment of ventricular tachycardia and symptomatic premature ventricular beats, and prevention of ventricular fibrillation.
Marketing Status approved; investigational
ATC Code C01BB02
DrugBank ID DB00379
KEGG ID D08215
MeSH ID D008801
PubChem ID 4178
TTD Drug ID D0X0RI
NDC Product Code Not Available
UNII 1U511HHV4Z
Synonyms Mexiletine | Novo-Mexiletine | Novo Mexiletine | Mexiletine Hydrochloride | Mexitil | Mexitil PL | Mexityl | KO-1173 | KO 1173 | KO1173 | KOE-1173 | KOE 1173 | KOE1173 | Mexiletene
Chemical Information
Molecular Formula C11H17NO
CAS Registry Number 31828-71-4
SMILES CC1=C(C(=CC=C1)C)OCC(C)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dysphagia07.01.06.003--
Dyspnoea02.11.05.003; 22.02.01.004--
Erythema multiforme10.01.03.015; 23.03.01.003--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal pain07.01.05.005--
Hallucination19.10.04.003--
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Hiccups07.01.06.009; 22.12.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypoaesthesia17.02.06.023; 23.03.03.081--Not Available
Hypotension24.06.03.002--
Leukopenia01.02.02.001--Not Available
Libido decreased21.03.02.005; 19.08.03.001--
Liver function test abnormal13.03.04.030--Not Available
Loss of consciousness17.02.04.004--Not Available
Lung infiltration22.01.02.004--Not Available
Malaise08.01.01.003--
Menopausal symptoms21.02.02.002--Not Available
Muscle spasms15.05.03.004--
Myelofibrosis16.21.03.001; 01.13.03.005--Not Available
Myeloid metaplasia01.13.03.004; 16.21.03.005--Not Available
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Neutropenia01.02.03.004--Not Available
Nystagmus17.02.02.006; 06.05.02.006--
Oedema14.05.06.010; 08.01.07.006--Not Available
The 2th Page    First    Pre   2 3 4    Next   Last    Total 4 Pages