Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Unexplained chronic cough | Refractory chronic cough | Coughs
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02511Siponimod--
BADD_D02515Pexidartinib0.000817%
BADD_D02524Ivosidenib0.001768%
BADD_D02526Larotrectinib0.000627%
BADD_D02527Abrocitinib--
BADD_D02539Calcium0.001253%
BADD_D02540Capmatinib0.000851%
BADD_D02549Deucravacitinib0.001640%
BADD_D02553Entrectinib0.000302%
BADD_D02554Fedratinib0.000437%
BADD_D02555Fenfluramine--
BADD_D02556Ferrous cation0.004392%
BADD_D02558Gadolinium cation (3+)-
BADD_D02569Magnesium0.000294%
BADD_D02570Maralixibat0.003544%
BADD_D02575Omadacycline0.000049%
BADD_D02577Oseltamivir acid0.003668%
BADD_D02580Ozanimod0.008318%
BADD_D02585Pralsetinib0.000302%
BADD_D02591Ripretinib0.000985%
BADD_D02593Selpercatinib0.000246%
BADD_D02596Sotorasib0.001063%
BADD_D02603Tucatinib0.001007%
BADD_D02608Voclosporin0.000820%
BADD_D02609Zanubrutinib0.000604%
BADD_D02611Aluminum hydroxide--
BADD_D02615Bilastine--
BADD_D02624Iodine--
BADD_D02627Methyl salicylate--
BADD_D02635Rupatadine--
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ADReCS-Target
ADR Term Drug Name Target