Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Malaise
ADR ID BADD_A02640
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.003      Malaise
Description A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. [CTCAE]
MedDRA Code 10025482
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Feeling sick | Feeling unwell | Felt generally ill | Felt ill | General malaise | Generally off-colour | Generally unwell | Ill feeling | Malaise | Malaise and fatigue | Sickness feeling | Stamina decreased | Unwell | Generally off-color | Post-exertional malaise | Physically unwell
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01852Progesterone--
BADD_D01856Propafenone0.001547%
BADD_D01858Propagermanium--
BADD_D01872Protriptyline--
BADD_D01873Protriptyline hydrochloride--
BADD_D01874Prucalopride0.005225%
BADD_D01876Pseudoephedrine--
BADD_D01880Pyrazinamide0.001540%
BADD_D01886Pyrimethamine0.000482%
BADD_D01888Quetiapine--
BADD_D01889Quetiapine fumarate--
BADD_D01890Quinapril--
BADD_D01891Quinapril hydrochloride--
BADD_D01892Quinaprilat--
BADD_D01898Rabeprazole--
BADD_D01903Raloxifene0.001154%
BADD_D01906Raltegravir potassium--
BADD_D01907Raltitrexed--
BADD_D01909Ramipril0.004196%
BADD_D01910Ramiprilat--
BADD_D01913Ranitidine--
BADD_D01914Ranitidine hydrochloride--
BADD_D01916Rasagiline mesylate--
BADD_D01919Reboxetine--
BADD_D01921Regadenoson0.003155%
BADD_D01922Regorafenib0.009995%
BADD_D01924Repaglinide0.006120%
BADD_D01932Rho (d) immune globulin (human)--
BADD_D01933Ribavirin0.736181%
BADD_D01935Rifabutin0.032082%
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