Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Deferasirox
Drug ID BADD_D00594
Description Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.
Indications and Usage For the treatment of chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients 2 years of age and older.
Marketing Status approved; investigational
ATC Code V03AC03
DrugBank ID DB01609
KEGG ID D03669
MeSH ID D000077588
PubChem ID 214348
TTD Drug ID D0Q5UQ
NDC Product Code 49706-2103; 59285-010; 66039-871; 31722-030; 43598-852; 45963-454; 45963-456; 67877-552; 69238-1703; 69452-161; 69539-200; 70700-271; 70771-1410; 70771-1471; 58032-2017; 0078-0468; 0078-0469; 31722-013; 43598-854; 69238-1488; 69452-159; 69539-023; 46708-410; 57664-768; 62332-324; 62756-568; 69539-021; 69539-073; 69539-199; 62332-412; 67877-550; 67877-553; 69097-391; 69097-560; 69539-022; 70771-1472; 65727-037; 0078-0655; 42806-371; 43598-851; 67877-554; 68462-495; 68462-496; 69097-392; 70710-1012; 62512-0078; 0078-0470; 0078-0654; 0078-0720; 31722-029; 43598-856; 46708-411; 46708-412; 69097-393; 69238-1486; 69539-303; 70710-1276; 72205-176; 14501-0049; 63278-1070; 65085-0063; 66022-0301; 0078-0656; 31722-031; 43598-855; 57664-769; 62332-325; 62756-569; 69539-075; 70710-1011; 72205-075; 72647-372; 74436-0323; 31722-012; 43598-853; 62332-326; 62332-411; 62756-570; 68462-494; 69097-570; 69238-1487; 69238-1702; 69238-1704; 70710-1013; 70771-1411; 70771-1473; 0591-3853; 72647-371; 0591-2961; 11722-040; 53104-7713; 59651-419; 0078-0727; 42806-372; 46708-324; 46708-325; 57664-770; 67877-549; 69539-074; 70700-270; 72205-076; 65015-738; 0078-0713; 31722-011; 42806-373; 45963-455; 46708-326; 62332-410; 67877-551; 69097-550; 69452-160; 70700-269; 70710-1275; 70710-1277; 70771-1409; 72647-373; 65372-1164
UNII V8G4MOF2V9
Synonyms Deferasirox | 4-(3,5-Bis-(2-hydroxyphenyl)-(1,2,4)-triazol-1-yl)benzoic acid | ICL 670A | ICL-670A | ICL670A | ICL-670 | ICL670 | ICL 670 | Exjade
Chemical Information
Molecular Formula C21H15N3O4
CAS Registry Number 201530-41-8
SMILES C1=CC=C(C(=C1)C2=NN(C(=N2)C3=CC=CC=C3O)C4=CC=C(C=C4)C(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pain in extremity15.03.04.0100.035067%
Pancreatic disorder07.18.02.0010.001239%Not Available
Pancreatitis07.18.01.0010.014250%
Pancreatitis acute07.18.01.0020.005576%Not Available
Pancytopenia01.03.03.0030.016109%Not Available
Paralysis17.01.04.0040.002478%Not Available
Paroxysmal nocturnal haemoglobinuria20.02.01.022; 01.06.03.003; 24.01.01.0150.001239%Not Available
Peliosis hepatis09.01.07.0100.001239%Not Available
Peptic ulcer07.04.07.0010.001859%Not Available
Periorbital oedema23.04.01.002; 10.01.05.010; 06.08.03.0170.001239%
Petit mal epilepsy17.12.04.0010.001239%Not Available
Pharyngitis07.05.07.004; 22.07.03.004; 11.01.13.003--
Platelet disorder01.08.03.0010.001859%Not Available
Pleural effusion22.05.02.002--
Polyuria20.02.03.0020.004585%Not Available
Pre-eclampsia24.08.07.002; 20.01.08.002; 18.02.03.0020.001239%Not Available
Pregnancy18.08.02.0040.012391%Not Available
Proctalgia07.03.02.0010.002726%
Productive cough22.02.03.005--
Proteinuria20.02.01.0110.038289%
Pruritus23.03.12.001--
Psychomotor hyperactivity19.11.02.003; 17.01.02.011--Not Available
Pulmonary alveolar haemorrhage24.07.01.015; 22.01.02.0050.001859%Not Available
Pulmonary hypertension24.08.03.002; 22.06.01.0010.004337%
Pulmonary oedema22.01.03.003; 02.05.02.0030.006815%
Purpura24.07.06.005; 23.06.01.004; 01.01.04.0030.003098%
Pyrexia08.05.02.0030.121186%
Rash23.03.13.0010.221926%Not Available
Rash maculo-papular23.03.13.0040.004337%
Rash papular23.03.13.017--Not Available
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