Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Haemolytic uraemic syndrome
ADR ID BADD_A01934
ADR Hierarchy
01      Blood and lymphatic system disorders
01.06      Haemolyses and related conditions
01.06.02      Anaemias haemolytic mechanical factor
01.06.02.001      Haemolytic uraemic syndrome
20      Renal and urinary disorders
20.01      Renal disorders (excl nephropathies)
20.01.03      Renal failure and impairment
20.01.03.011      Haemolytic uraemic syndrome
Description A syndrome that is associated with microvascular diseases of the KIDNEY, such as RENAL CORTICAL NECROSIS. It is characterized by hemolytic anemia (ANEMIA, HEMOLYTIC); THROMBOCYTOPENIA; and ACUTE RENAL FAILURE. [MeSH]
MedDRA Code 10018932
MeSH ID D006463
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Haemolytic uraemic syndrome | Haemolytic-uraemic syndrome | Hemolytic uremic syndrome | Hemolytic-uremic syndrome | HUS | Syndrome hemolytic uremic | Syndrome haemolytic uraemic | Hemolytic-Uremic Syndrome | Hemolytic Uremic Syndrome | Syndrome, Hemolytic-Uremic | Gasser's Syndrome | Gassers Syndrome | Gasser Syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00014Abiraterone0.000334%
BADD_D00032Acetylcysteine0.000149%
BADD_D00039Acyclovir--
BADD_D00142Anastrozole0.000318%
BADD_D00151Apixaban0.000108%
BADD_D00281Bleomycin sulfate--
BADD_D00364Carboplatin0.000224%
BADD_D00367Carfilzomib0.000839%
BADD_D00474Cisplatin0.000168%
BADD_D00504Clopidogrel0.000086%
BADD_D00549Cyclophosphamide--
BADD_D00551Cyclosporine0.000166%
BADD_D00643Diamminedichloroplatinum--
BADD_D00844Ethinyl estradiol--
BADD_D00858Everolimus0.000229%
BADD_D00864Ezetimibe0.000063%
BADD_D00871Felbamate--
BADD_D00931Fluorouracil0.000184%
BADD_D01003Ganciclovir--
BADD_D01004Ganciclovir sodium--
BADD_D01009Gemcitabine0.001063%
BADD_D01010Gemcitabine hydrochloride--
BADD_D01133Ifosfamide--
BADD_D01232Ketorolac--
BADD_D01233Ketorolac tromethamine--
BADD_D01449Metronidazole0.000066%
BADD_D01478Mitomycin--
BADD_D01633Oxaliplatin0.000560%
BADD_D01653Paclitaxel0.000168%
BADD_D01687Pazopanib0.000168%
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