Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Headache
ADR ID BADD_A01965
ADR Hierarchy
17      Nervous system disorders
17.14      Headaches
17.14.01      Headaches NEC
17.14.01.001      Headache
Description A disorder characterized by a sensation of marked discomfort in various parts of the head, not confined to the area of distribution of any nerve. [CTCAE] The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS. [MeSH]
MedDRA Code 10019211
MeSH ID D006261; D020773
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cephalalgia | Cephalalgia or cephalgia | Cephalgia | Forehead headache | Head pain | Head throbbing | Headache | Headache (except migraine) aggravated | Headache discomfort | Headache dull | Headache fullness | Headache NOS | Headache NOS aggravated | Headache occurring | Headache temporal | Headache transient | Hemicephalgia | Hemicrania | Nocturnal headache | Pain head | Pounding in head | Temporal headache | Headache aggravated | Frontal headache | Occipital headache | Parietal headache | Headache unilateral | Drug-induced headache | Frequent headaches | Chronic headaches | Headache (excl migraine) aggravated | Throbbing headache | Intermittent headache | Retroauricular pain | Headache recurrent | Hemicephalalgia | Nuchal headache | Persistent headache | Barometric pressure headache | Nummular headache | Headaches | Head Pain | Head Pains | Pain, Head | Pains, Head | Cephalodynia | Cephalodynias | Cranial Pain | Cranial Pains | Pain, Cranial | Pains, Cranial | Cephalalgias | Cephalgias | Generalized Headache | Generalized Headaches | Headache, Generalized | Headaches, Generalized | Ocular Headache | Headache, Ocular | Headaches, Ocular | Ocular Headaches | Orthostatic Headache | Headache, Orthostatic | Headaches, Orthostatic | Orthostatic Headaches | Vertex Headache | Headache, Vertex | Headaches, Vertex | Vertex Headaches | Retro-Ocular Headache | Headache, Retro-Ocular | Headaches, Retro-Ocular | Retro Ocular Headache | Retro-Ocular Headaches | Sharp Headache | Headache, Sharp | Headaches, Sharp | Sharp Headaches | Throbbing Headache | Headache, Throbbing | Headaches, Throbbing | Throbbing Headaches | Unilateral Headache | Headache, Unilateral | Headaches, Unilateral | Unilateral Headaches | Bilateral Headache | Bilateral Headaches | Headache, Bilateral | Headaches, Bilateral | Periorbital Headache | Headache, Periorbital | Headaches, Periorbital | Periorbital Headaches
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02579Oxymetazoline0.017368%
BADD_D02580Ozanimod0.060085%
BADD_D02583Pitolisant0.006406%
BADD_D02584Ponesimod0.000241%
BADD_D02589Revefenacin0.000317%
BADD_D02590Rimegepant0.001925%
BADD_D02591Ripretinib0.002731%
BADD_D02593Selpercatinib0.000739%
BADD_D02595Solriamfetol0.003034%
BADD_D02597Tapinarof-
BADD_D02598Tazemetostat0.000571%
BADD_D02600Tivozanib0.000246%
BADD_D02603Tucatinib0.004332%
BADD_D02604Ubrogepant0.001052%
BADD_D02606Vibegron-
BADD_D02607Viloxazine0.000318%
BADD_D02608Voclosporin0.006968%
BADD_D02609Zanubrutinib--
BADD_D02611Aluminum hydroxide--
BADD_D02613Astemizole--
BADD_D02615Bilastine--
BADD_D02616Calcium carbonate--
BADD_D02619Dienogest--
BADD_D02621Ferrous fumarate--
BADD_D02628Myristamidopropyl dimethylamine--
BADD_D02632Profenamine--
BADD_D02635Rupatadine--
BADD_D02636Sulfisoxazole--
BADD_D02637Terfenadine--
BADD_D02639Tryptophan--
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ADReCS-Target
ADR Term Drug Name Target